C4BPB

Across TCGA cell cohorts, C4BPB RNA expression is significantly associated with the go_rna of many other GO terms, with 1,439 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C4BPB-associated GO terms across cancer lineages are Positive regulation of CD4-positive, alpha-beta T cell proliferation, Regulation of type III interferon production, and Negative regulation of protein tyrosine kinase activity. Each is linked with C4BPB in more than 7 cancer types. Because this analysis shows association rather than direction, both C4BPB-to-partner and partner-to-C4BPB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of CD4-positive, alpha-beta T cell proliferation grouped by C4BPB-low versus C4BPB-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C4BPB→partner) and Y-score (partner→C4BPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Positive regulation of CD4-positive, alpha-beta T cell proliferation →	+0.283	+3.031	<.001	<.001	3	8
LARGE_INTESTINE	Regulation of type III interferon production →	+0.509	+2.201	.005	.001	2	8
SOFT_TISSUE	Negative regulation of protein tyrosine kinase activity →	+0.081	+0.442	<.001	.009	3	7
OVARY	Positive regulation of cell growth involved in cardiac muscle cell development →	+1.018	+1.261	<.001	.007	3	7
PANCREAS	Negative regulation of thymocyte apoptotic process →	+1.158	+2.906	.005	<.001	3	7
PANCREAS	Regulation of viral genome replication →	+0.129	+2.821	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,439 associations by consensus.

Positive regulation of CD4-positive, alpha-beta T cell proliferation by C4BPB expression — LARGE_INTESTINE

Explore this box plot interactively →