C4BPB

Across TCGA cell cohorts, C4BPB mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible C4BPB-associated genes across cancer lineages are FTHL17, OR8J3, and FAM71B. Each is linked with C4BPB in more than 1 cancer types. Because this analysis shows association rather than direction, both C4BPB-to-partner and partner-to-C4BPB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FTHL17 grouped by C4BPB-low versus C4BPB-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C4BPB→partner) and Y-score (partner→C4BPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	FTHL17 →	+0.036	+5.807	<.001	.001	3	1
OVARY	OR8J3 →	+0.026	+5.807	<.001	.001	3	1
OVARY	FAM71B →	+0.006	+5.807	<.001	.001	3	1
OVARY	OR1L1 →	+0.036	+5.196	<.001	.005	3	1
OVARY	IQCF2 →	+0.055	+5.196	<.001	.005	3	1
OVARY	ODF4 →	+0.042	+5.196	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

FTHL17 by C4BPB expression — OVARY

Explore this box plot interactively →