Across TCGA patient cohorts, C4B mutation is significantly associated with the RNA expression of many other genes, with 248 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible C4B-associated genes across cancer lineages are SSX9P, MIR3132, and FAM204DP. Each is linked with C4B in more than 1 cancer types. Because this analysis shows association rather than direction, both C4B-to-partner and partner-to-C4B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C4B→partner) and Y-score (partner→C4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	SSX9P →	+1.028	+4.266	<.001	.003	3	2
UCEC	MIR3132 →	+0.440	+2.560	.007	.007	3	2
SKCM	FAM204DP →	+0.037	+2.244	.002	.007	3	2
BLCA	ABCD1P4 →	+0.375	+4.320	<.001	.002	3	2
UCEC	MIR7976 →	+0.538	+2.868	<.001	.006	3	2
UCEC	API5P2 →	+0.100	+2.449	.008	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 248 associations by consensus.

Exploration

C4B survival (RNA) · tumor vs normal (RNA) · all C4B data types