C3orf84

Across TCGA patient cohorts, C3orf84 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,767 significant associations in total. STAD shows the largest number of these associations.

The most reproducible C3orf84-associated GO terms across cancer lineages are Alpha-beta T cell activation, Antigen receptor-mediated signaling pathway, and Nucleoside triphosphate metabolic process. Each is linked with C3orf84 in more than 16 cancer types. Because this analysis shows association rather than direction, both C3orf84-to-partner and partner-to-C3orf84 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Alpha-beta T cell activation grouped by C3orf84-low versus C3orf84-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf84→partner) and Y-score (partner→C3orf84) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Alpha-beta T cell activation →	+0.060	+0.138	<.001	<.001	3	17
STAD	Antigen receptor-mediated signaling pathway →	+0.062	+0.140	<.001	<.001	3	17
STAD	Nucleoside triphosphate metabolic process →	+0.064	+0.170	<.001	<.001	3	16
STAD	T cell activation involved in immune response →	+0.061	+0.158	<.001	<.001	3	16
STAD	Positive regulation of leukocyte cell-cell adhesion →	+0.064	+0.144	<.001	<.001	3	16
STAD	Regulation of lymphocyte differentiation →	+0.063	+0.166	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,767 associations by consensus.

Alpha-beta T cell activation by C3orf84 expression — STAD

Explore this box plot interactively →