C3orf84

Across TCGA pan-cancer cohorts, C3orf84 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of C3orf84’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where C3orf84 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types C3orf84 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

KIRC, THCA, and KIRP are the cancer types where C3orf84 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C3orf84 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	+0.056	<.001	10	view →
THCA	All	All	−0.037	.007	3	view →
KIRP	All	All	+0.070	.003	2	view →
LUSC	Male	II,III,IV	−0.040	.047	2	view →
PRAD	All	All	+0.032	.011	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

C3orf84–KIRC

Open the KIRC breakdown →