C3orf84

Across TCGA patient cohorts, C3orf84 mutation is significantly associated with the RNA expression of many other genes, with 1,064 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C3orf84-associated genes across cancer lineages are GRPEL2P2, RNU4-37P, and DAZ2. Each is linked with C3orf84 in more than 1 cancer types. Because this analysis shows association rather than direction, both C3orf84-to-partner and partner-to-C3orf84 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GRPEL2P2 grouped by C3orf84-low versus C3orf84-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf84→partner) and Y-score (partner→C3orf84) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GRPEL2P2 →	+0.255	+4.910	<.001	.002	3	2
HNSC	RNU4-37P →	+0.878	+7.954	<.001	.008	3	1
SKCM	DAZ2 →	+0.096	+4.440	<.001	.006	3	1
SKCM	MIR190B →	+0.321	+4.771	<.001	.006	3	1
SKCM	SLC25A51P1 →	+0.041	+4.680	<.001	.007	3	1
SKCM	MIR1226 →	+0.369	+4.513	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,064 associations by consensus.

GRPEL2P2 by C3orf84 expression — COAD

Explore this box plot interactively →