C3orf84

Across TCGA cell cohorts, C3orf84 RNA expression is significantly associated with the mutation status of many other genes, with 49 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible C3orf84-associated genes across cancer lineages are SPEF2, RYR1, and SPIRE2. Each is linked with C3orf84 in more than 1 cancer types. Because this analysis shows association rather than direction, both C3orf84-to-partner and partner-to-C3orf84 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPEF2 grouped by C3orf84-low versus C3orf84-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf84→partner) and Y-score (partner→C3orf84) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	SPEF2 →	+4.357	+0.020	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	RYR1 →	+4.357	+0.020	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	SPIRE2 →	+5.357	+0.026	.003	<.001	3	1
BREAST	KRR1 →	+5.169	+0.058	.005	<.001	3	1
BREAST	FKBP15 →	+5.169	+0.058	.005	<.001	3	1
BREAST	GREB1L →	+5.169	+0.051	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

SPEF2 by C3orf84 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →