C3orf80

Across TCGA patient cohorts, C3orf80 protein abundance is significantly associated with the RNA expression of many other genes, with 150 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible C3orf80-associated genes across cancer lineages are POLR3H, R3HCC1, and GALK1. Each is linked with C3orf80 in more than 1 cancer types. Because this analysis shows association rather than direction, both C3orf80-to-partner and partner-to-C3orf80 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C3orf80 versus POLR3H in BRCA, with a Pearson correlation of 0.91.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf80→partner) and Y-score (partner→C3orf80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	POLR3H →	+0.690	+1.982	<.001	.003	3	1
BRCA	R3HCC1 →	+0.282	+1.982	.001	.003	3	1
BRCA	GALK1 →	+0.859	+1.982	.004	.003	3	1
BRCA	UNC119 →	+0.740	+1.982	.007	.003	3	1
BRCA	PODXL2 →	+3.275	+1.982	<.001	.003	3	1
BRCA	MRPS7 →	+0.985	+1.982	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 150 associations by consensus.

C3orf80 vs POLR3H — BRCA

Explore this scatter interactively →