C3orf80

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C3orf80 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,834 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C3orf80-associated GO terms across cancer lineages are Aerobic electron transport chain, ATP synthesis coupled electron transport, and Mitochondrial ATP synthesis coupled electron transport. Each is linked with C3orf80 in more than 8 cancer types. Because this analysis shows association rather than direction, both C3orf80-to-partner and partner-to-C3orf80 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic electron transport chain grouped by C3orf80-low versus C3orf80-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf80→partner) and Y-score (partner→C3orf80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCAerobic electron transport chain →+0.092+0.267.005.00439
LUNG_NSCLC_LUSCATP synthesis coupled electron transport →+0.097+0.255.005.00539
LUNG_NSCLC_LUSCMitochondrial ATP synthesis coupled electron transport →+0.097+0.255.005.00539
OESOPHAGUSCytoplasmic translation →+0.106+0.758.005.00637
BLOOD_MyelomaRespiratory electron transport chain →+0.069+0.420.004.00428
LUNG_NSCLC_LUADSpermatid development →-0.032-0.541<.001.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,834 associations by consensus.

Aerobic electron transport chain by C3orf80 expression — LUNG_NSCLC_LUSC

Box plot of Aerobic electron transport chain in C3orf80-low vs C3orf80-high samples in LUNG_NSCLC_LUSC.

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Exploration