Across TCGA patient cohorts, C3orf56 mutation is significantly associated with the RNA expression of many other genes, with 799 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C3orf56-associated genes across cancer lineages are NTAN1, MON1A, and CTU2. Each is linked with C3orf56 in more than 1 cancer types. Because this analysis shows association rather than direction, both C3orf56-to-partner and partner-to-C3orf56 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf56→partner) and Y-score (partner→C3orf56) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NTAN1 →	+0.640	+2.616	<.001	.005	3	2
UCEC	MON1A →	+0.323	+3.332	.008	.005	3	2
UCEC	CTU2 →	+0.430	+2.332	.002	.003	3	2
UCEC	NCAPH2 →	+0.587	+3.839	<.001	<.001	3	2
UCEC	MSANTD3 →	+0.473	+2.332	.008	.003	3	2
BLCA	RN7SL275P →	+0.129	+4.213	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 799 associations by consensus.

Exploration

C3orf56 survival (RNA) · tumor vs normal (RNA) · all C3orf56 data types