C3orf52

Across TCGA patient cohorts, C3orf52 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,896 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C3orf52-associated proteins across cancer lineages are KIAA1522, SND1, and MVK. Each is linked with C3orf52 in more than 3 cancer types. Because this analysis shows association rather than direction, both C3orf52-to-partner and partner-to-C3orf52 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C3orf52 versus KIAA1522 in BRCA, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf52→partner) and Y-score (partner→C3orf52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KIAA1522 →	+0.310	+1.164	.001	<.001	3	4
BRCA	SND1 →	-0.296	-1.210	<.001	<.001	3	3
COAD	MVK →	+0.377	+0.790	<.001	<.001	3	3
OV	NEDD4 →	+0.415	+0.540	.004	.002	3	3
GBM	PDLIM1 →	+0.592	+0.562	.001	.002	3	3
GBM	PLAU →	+0.816	+0.657	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,896 associations by consensus.

C3orf52 vs KIAA1522 — BRCA

Explore this scatter interactively →