C3orf52

Across TCGA cell cohorts, C3orf52 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,230 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C3orf52-associated GO terms across cancer lineages are Positive regulation of extracellular exosome assembly, Rho protein signal transduction, and Actin filament organization. Each is linked with C3orf52 in more than 10 cancer types. Because this analysis shows association rather than direction, both C3orf52-to-partner and partner-to-C3orf52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of extracellular exosome assembly grouped by C3orf52-low versus C3orf52-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf52→partner) and Y-score (partner→C3orf52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of extracellular exosome assembly →	+0.193	+1.524	<.001	<.001	3	11
PANCREAS	Rho protein signal transduction →	+0.134	+1.199	<.001	<.001	3	11
BONE	Actin filament organization →	+0.117	+1.661	<.001	<.001	3	11
BONE	Endothelial cell development →	+0.167	+1.870	<.001	<.001	3	10
PANCREAS	Negative regulation of supramolecular fiber organization →	+0.067	+1.040	<.001	<.001	3	10
BONE	Regulation of extrinsic apoptotic signaling pathway →	+0.079	+1.705	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,230 associations by consensus.

Positive regulation of extracellular exosome assembly by C3orf52 expression — BONE

Explore this box plot interactively →