C3orf52

Across TCGA cell cohorts, C3orf52 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible C3orf52-associated genes across cancer lineages are GP9, OR2G6, and SLC22A6. Each is linked with C3orf52 in more than 1 cancer types. Because this analysis shows association rather than direction, both C3orf52-to-partner and partner-to-C3orf52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GP9 grouped by C3orf52-low versus C3orf52-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf52→partner) and Y-score (partner→C3orf52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	GP9 →	+0.076	+5.781	<.001	.001	3	1
BREAST	OR2G6 →	+0.023	+5.169	<.001	.005	3	1
LUNG_NSCLC_LUAD	SLC22A6 →	+0.006	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

GP9 by C3orf52 expression — BREAST

Explore this box plot interactively →