C3orf49

Across TCGA patient cohorts, C3orf49 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,081 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible C3orf49-associated proteins across cancer lineages are NR2C2, SETMAR, and S100A12. Each is linked with C3orf49 in more than 4 cancer types. Because this analysis shows association rather than direction, both C3orf49-to-partner and partner-to-C3orf49 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C3orf49 versus NR2C2 in HNSC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf49→partner) and Y-score (partner→C3orf49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NR2C2 →	+0.282	+0.527	<.001	.001	3	5
HNSC	SETMAR →	+0.402	+0.590	<.001	<.001	3	5
LUAD	S100A12 →	-1.011	-0.387	.004	.002	3	4
GBM	SDF2L1 →	-0.333	-0.393	<.001	<.001	3	4
LSCC	H1-0 →	-0.575	-0.443	.005	<.001	3	4
PDAC	YME1L1 →	-0.344	-0.318	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,081 associations by consensus.

C3orf49 vs NR2C2 — HNSC

Explore this scatter interactively →