C3orf38

Across TCGA patient cohorts, C3orf38 protein abundance is significantly associated with the RNA expression of many other genes, with 6,683 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C3orf38-associated genes across cancer lineages are PREX1, CDH26, and NXPE3. Each is linked with C3orf38 in more than 3 cancer types. Because this analysis shows association rather than direction, both C3orf38-to-partner and partner-to-C3orf38 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C3orf38 versus PREX1 in BRCA, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf38→partner) and Y-score (partner→C3orf38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PREX1 →	+1.406	+0.322	<.001	<.001	3	4
LSCC	CDH26 →	-0.865	-0.149	.009	.007	3	3
UCEC	NXPE3 →	+0.485	+0.144	.001	.001	3	3
UCEC	AKT3-IT1 →	+0.927	+0.162	<.001	.008	3	3
BRCA	OGG1 →	+0.482	+0.321	<.001	<.001	3	3
OV	CCDC66 →	+0.450	+0.226	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,683 associations by consensus.

C3orf38 vs PREX1 — BRCA

Explore this scatter interactively →