C3orf22

Across TCGA patient cohorts, C3orf22 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,011 significant associations in total. STAD shows the largest number of these associations.

The most reproducible C3orf22-associated GO terms across cancer lineages are Internal protein amino acid acetylation, Inner mitochondrial membrane organization, and Obsolete histone modification. Each is linked with C3orf22 in more than 24 cancer types. Because this analysis shows association rather than direction, both C3orf22-to-partner and partner-to-C3orf22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Internal protein amino acid acetylation grouped by C3orf22-low versus C3orf22-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf22→partner) and Y-score (partner→C3orf22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Internal protein amino acid acetylation →	+0.063	+0.091	<.001	<.001	3	25
STAD	Inner mitochondrial membrane organization →	+0.054	+0.071	<.001	<.001	3	25
ESCA	Obsolete histone modification →	+0.053	+0.066	<.001	<.001	3	25
STAD	Protein stabilization →	+0.050	+0.064	<.001	<.001	3	24
STAD	Positive regulation of DNA repair →	+0.048	+0.082	<.001	<.001	3	24
STAD	Regulation of DNA repair →	+0.050	+0.077	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,011 associations by consensus.

Internal protein amino acid acetylation by C3orf22 expression — ESCA

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