C3orf14

Across TCGA patient cohorts, C3orf14 mutation is significantly associated with the RNA expression of many other genes, with 1,098 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C3orf14-associated genes across cancer lineages are FAT1P1, RNA5SP192, and CCL5. Each is linked with C3orf14 in more than 1 cancer types. Because this analysis shows association rather than direction, both C3orf14-to-partner and partner-to-C3orf14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAT1P1 grouped by C3orf14-low versus C3orf14-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf14→partner) and Y-score (partner→C3orf14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	FAT1P1 →	+0.086	+6.018	<.001	.002	3	2
SKCM	RNA5SP192 →	+0.336	+7.485	<.001	<.001	3	2
UCEC	CCL5 →	+1.279	+2.606	.002	.006	3	1
UCEC	MIR98 →	+0.479	+3.386	<.001	<.001	3	1
UCEC	MIR6129 →	+0.548	+2.496	<.001	.001	3	1
UCEC	H3C8 →	+0.844	+3.330	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,098 associations by consensus.

FAT1P1 by C3orf14 expression — BLCA

Explore this box plot interactively →