Across TCGA patient cohorts, C2orf91 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. COAD shows the largest number of these associations.

The most reproducible C2orf91-associated genes across cancer lineages are RNU6-1289P, MIR598, and FTLP16. Each is linked with C2orf91 in more than 1 cancer types. Because this analysis shows association rather than direction, both C2orf91-to-partner and partner-to-C2orf91 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf91→partner) and Y-score (partner→C2orf91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-1289P →	+0.625	+5.357	<.001	.006	3	1
COAD	MIR598 →	+0.609	+5.357	<.001	.006	3	1
COAD	FTLP16 →	+0.145	+5.283	<.001	.006	3	1
COAD	HMGB1P25 →	+0.151	+5.435	.003	.005	3	1
COAD	H2AZP5 →	+0.219	+5.283	.009	.006	3	1
COAD	RNU6-176P →	+0.926	+5.080	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

C2orf91 survival (RNA) · tumor vs normal (RNA) · all C2orf91 data types