C2orf83

Across TCGA patient cohorts, C2orf83 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,689 significant associations in total. STAD shows the largest number of these associations.

The most reproducible C2orf83-associated GO terms across cancer lineages are Positive regulation of DNA biosynthetic process, Signal transduction in response to DNA damage, and Regulation of DNA biosynthetic process. Each is linked with C2orf83 in more than 14 cancer types. Because this analysis shows association rather than direction, both C2orf83-to-partner and partner-to-C2orf83 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA biosynthetic process grouped by C2orf83-low versus C2orf83-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf83→partner) and Y-score (partner→C2orf83) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA biosynthetic process →	+0.062	+0.166	<.001	<.001	3	15
STAD	Signal transduction in response to DNA damage →	+0.063	+0.159	<.001	<.001	3	14
STAD	Regulation of DNA biosynthetic process →	+0.063	+0.162	<.001	<.001	3	14
STAD	Protein-RNA complex organization →	+0.067	+0.177	<.001	<.001	3	14
STAD	Signal transduction by p53 class mediator →	+0.061	+0.164	<.001	<.001	3	14
STAD	Extrinsic apoptotic signaling pathway via death domain receptors →	+0.056	+0.178	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,689 associations by consensus.

Positive regulation of DNA biosynthetic process by C2orf83 expression — STAD

Explore this box plot interactively →