C2orf83

Across TCGA patient cohorts, C2orf83 mutation is significantly associated with the RNA expression of many other genes, with 208 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C2orf83-associated genes across cancer lineages are RNU6-166P, RNU6-225P, and RNU6-440P. Each is linked with C2orf83 in more than 1 cancer types. Because this analysis shows association rather than direction, both C2orf83-to-partner and partner-to-C2orf83 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-166P grouped by C2orf83-low versus C2orf83-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf83→partner) and Y-score (partner→C2orf83) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-166P →	+0.343	+7.640	<.001	.009	3	2
BLCA	RNU6-225P →	+0.593	+7.640	<.001	.009	3	2
BLCA	RNU6-440P →	+0.352	+7.640	<.001	.009	3	2
LUSC	RNU6-197P →	+0.447	+5.404	<.001	.005	3	2
UCEC	RNU6-358P →	+0.510	+3.548	<.001	.001	3	2
LUAD	PTMAP15 →	+0.313	+5.343	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 208 associations by consensus.

RNU6-166P by C2orf83 expression — BLCA

Explore this box plot interactively →