C2orf83

Across TCGA cell cohorts, C2orf83 RNA expression is significantly associated with the go_rna of many other GO terms, with 332 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible C2orf83-associated GO terms across cancer lineages are Protein targeting to lysosome, Regulation of amyloid-beta clearance, and Cellular response to radiation. Each is linked with C2orf83 in more than 3 cancer types. Because this analysis shows association rather than direction, both C2orf83-to-partner and partner-to-C2orf83 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein targeting to lysosome grouped by C2orf83-low versus C2orf83-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf83→partner) and Y-score (partner→C2orf83) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein targeting to lysosome →	+0.083	+0.029	<.001	.008	3	4
UPPER_AERODIGESTIVE_TRACT	Regulation of amyloid-beta clearance →	+0.143	+0.029	<.001	.008	3	3
LUNG_SCLC	Cellular response to radiation →	+0.032	+0.026	.009	.002	3	3
LUNG_NSCLC_LUAD	Regulation of generation of precursor metabolites and energy →	+0.039	+0.025	<.001	.004	3	3
LUNG_NSCLC_LUAD	Establishment of protein localization to organelle →	+0.027	+0.019	.001	.007	3	3
LARGE_INTESTINE	Proteasomal ubiquitin-independent protein catabolic process →	+0.061	+0.026	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 332 associations by consensus.

Protein targeting to lysosome by C2orf83 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →