Across TCGA cell cohorts, C2orf78 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible C2orf78-associated genes across cancer lineages are GH2, ENPP5, and ACTB. Each is linked with C2orf78 in more than 1 cancer types. Because this analysis shows association rather than direction, both C2orf78-to-partner and partner-to-C2orf78 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf78→partner) and Y-score (partner→C2orf78) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	GH2 →	+0.113	+4.269	<.001	.005	3	1
SKIN	ENPP5 →	+0.721	+3.212	.008	.006	3	1
SKIN	ACTB →	+0.554	+3.299	.002	.004	3	1
LUNG_NSCLC_LUAD	TERB2 →	+0.008	+3.681	<.001	.009	3	1
LUNG_NSCLC_LUAD	DEFB4A →	+0.527	+3.145	<.001	.002	3	1
LUNG_NSCLC_LUAD	CCL19 →	+0.067	+3.150	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Exploration

C2orf78 survival (RNA) · tumor vs normal (RNA) · all C2orf78 data types