C2orf73

Across TCGA patient cohorts, C2orf73 mutation is significantly associated with the RNA expression of many other genes, with 2,079 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C2orf73-associated genes across cancer lineages are RNU7-90P, CFHR2, and H3P46. Each is linked with C2orf73 in more than 1 cancer types. Because this analysis shows association rather than direction, both C2orf73-to-partner and partner-to-C2orf73 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-90P grouped by C2orf73-low versus C2orf73-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf73→partner) and Y-score (partner→C2orf73) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU7-90P →	+0.255	+2.771	<.001	.003	3	2
HNSC	CFHR2 →	+0.049	+7.954	<.001	.008	3	1
BRCA	H3P46 →	+0.118	+7.731	<.001	.009	3	1
UCEC	YTHDF3-AS1 →	+0.696	+2.556	<.001	.001	3	1
UCEC	IGKV1OR2-118 →	+0.316	+2.785	<.001	<.001	3	1
UCEC	IGHV3OR16-8 →	+0.623	+3.191	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,079 associations by consensus.

RNU7-90P by C2orf73 expression — UCEC

Explore this box plot interactively →