C2orf69

Across TCGA patient cohorts, C2orf69 protein abundance is significantly associated with the RNA expression of many other genes, with 8,406 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C2orf69-associated genes across cancer lineages are HJURP, HSPD1, and TOP2A. Each is linked with C2orf69 in more than 4 cancer types. Because this analysis shows association rather than direction, both C2orf69-to-partner and partner-to-C2orf69 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C2orf69 versus HJURP in LUAD, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf69→partner) and Y-score (partner→C2orf69) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HJURP →	+0.924	+0.217	.003	.002	3	5
HNSC	HSPD1 →	+0.554	+0.137	.002	.005	3	5
LUAD	TOP2A →	+0.909	+0.214	.005	.001	3	4
LUAD	BUB1 →	+0.765	+0.209	.005	.002	3	4
BRCA	IFFO1 →	-0.688	-0.310	.001	<.001	3	4
LSCC	PSMD1 →	+0.323	+0.191	.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,406 associations by consensus.

C2orf69 vs HJURP — LUAD

Explore this scatter interactively →