Across TCGA patient cohorts, C2orf66 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,151 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible C2orf66-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway, and Nuclear-transcribed mRNA poly(A) tail shortening. Each is linked with C2orf66 in more than 28 cancer types. Because this analysis shows association rather than direction, both C2orf66-to-partner and partner-to-C2orf66 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf66→partner) and Y-score (partner→C2orf66) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.097	+0.625	<.001	<.001	2	29
DLBC	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.056	+0.134	.002	<.001	3	28
DLBC	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.078	+0.162	.001	<.001	3	27
UVM	Methylation →	+0.039	+0.367	<.001	<.001	3	27
DLBC	Maintenance of cell number →	+0.058	+0.209	<.001	<.001	3	27
SCLC	Obsolete DNA methylation →	+0.121	+0.540	<.001	.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,151 associations by consensus.

Exploration

C2orf66 survival (RNA) · tumor vs normal (RNA) · all C2orf66 data types