C2orf66

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C2orf66 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,939 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible C2orf66-associated GO terms across cancer lineages are Response to hydrostatic pressure, Negative regulation of nucleotide metabolic process, and Regulation of RNA splicing. Each is linked with C2orf66 in more than 8 cancer types. Because this analysis shows association rather than direction, both C2orf66-to-partner and partner-to-C2orf66 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf66→partner) and Y-score (partner→C2orf66) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINResponse to hydrostatic pressure →+0.109+0.326<.001<.00139
LIVERNegative regulation of nucleotide metabolic process →+0.122+0.110.001.00338
UPPER_AERODIGESTIVE_TRACTRegulation of RNA splicing →+0.074+0.271.005.00638
LIVERNegative regulation of purine nucleotide metabolic process →+0.122+0.110.001.00338
SKINAscending thin limb development →+0.200+0.304.003.00238
SKINMetanephric ascending thin limb development →+0.200+0.304.003.00238
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,939 associations by consensus.

Exploration