C2orf42

Across TCGA patient cohorts, C2orf42 mutation is significantly associated with the RNA expression of many other genes, with 3,996 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C2orf42-associated genes across cancer lineages are RN7SKP256, SLC25A31, and RNA5SP438. Each is linked with C2orf42 in more than 2 cancer types. Because this analysis shows association rather than direction, both C2orf42-to-partner and partner-to-C2orf42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP256 grouped by C2orf42-low versus C2orf42-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf42→partner) and Y-score (partner→C2orf42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP256 →	+0.136	+2.452	.006	.008	3	3
UCEC	SLC25A31 →	+0.095	+2.183	.003	.002	3	2
LUSC	RNA5SP438 →	+0.457	+4.625	<.001	.008	3	2
LUSC	KRTAP12-6P →	+0.141	+4.882	<.001	.005	3	2
BLCA	MORF4L1P6 →	+0.159	+7.640	<.001	.009	3	2
SKCM	HLTF-AS1 →	+0.078	+5.199	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,996 associations by consensus.

RN7SKP256 by C2orf42 expression — UCEC

Explore this box plot interactively →