Across TCGA cell cohorts, C2orf16 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,389 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible C2orf16-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Negative regulation of myoblast fusion, and Cytoskeleton-dependent cytokinesis. Each is linked with C2orf16 in more than 13 cancer types. Because this analysis shows association rather than direction, both C2orf16-to-partner and partner-to-C2orf16 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf16→partner) and Y-score (partner→C2orf16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.114	+0.384	<.001	.003	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.133	+0.453	<.001	.003	3	13
LUNG_SCLC	Cytoskeleton-dependent cytokinesis →	+0.073	+0.577	.001	.001	3	12
LUNG_SCLC	Cytokinesis →	+0.055	+0.409	.002	.005	3	12
STOMACH	Regulatory ncRNA-mediated gene silencing →	+0.076	+0.446	<.001	<.001	3	12
STOMACH	Endosomal transport →	+0.062	+0.473	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,389 associations by consensus.

Exploration

C2orf16 survival (RNA) · tumor vs normal (RNA) · all C2orf16 data types