C2orf15

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C2orf15 protein abundance is significantly associated with the RNA expression of many other genes, with 228 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible C2orf15-associated genes across cancer lineages are DHDH, ATF6, and EPX. Each is linked with C2orf15 in more than 1 cancer types. Because this analysis shows association rather than direction, both C2orf15-to-partner and partner-to-C2orf15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C2orf15 versus DHDH in BRCA, with a Pearson correlation of -0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf15→partner) and Y-score (partner→C2orf15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCADHDH →-1.391-0.891.001.00231
BRCAATF6 →+0.444+0.659.005.00131
BRCAEPX →-0.385-0.641.008.00531
BRCANR0B2 →-0.282-0.640.001.00931
BRCACTNNBL1 →+0.460+0.559.009.00831
BRCASTEAP2 →+1.370+0.565<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 228 associations by consensus.

C2orf15 vs DHDH — BRCA

Per-sample scatter of C2orf15 vs DHDH in BRCA (Pearson r = -0.75).

Explore this scatter interactively →

Exploration