C2orf15

Across TCGA patient cohorts, C2orf15 mutation is significantly associated with the RNA expression of many other genes, with 76 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C2orf15-associated genes across cancer lineages are C1QBPP1, LINC02647, and MTCO2P32. Each is linked with C2orf15 in more than 1 cancer types. Because this analysis shows association rather than direction, both C2orf15-to-partner and partner-to-C2orf15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1QBPP1 grouped by C2orf15-low versus C2orf15-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf15→partner) and Y-score (partner→C2orf15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C1QBPP1 →	+0.096	+4.621	<.001	.008	3	2
UCEC	LINC02647 →	+0.211	+5.335	<.001	.003	3	2
UCEC	MTCO2P32 →	+0.181	+5.877	<.001	.001	3	2
SKCM	RN7SL453P →	+0.106	+5.797	<.001	.001	3	1
UCEC	OR51A6P →	+0.076	+5.027	.002	.004	3	1
UCEC	MIR380 →	+0.689	+6.049	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 76 associations by consensus.

C1QBPP1 by C2orf15 expression — UCEC

Explore this box plot interactively →