C2orf15

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C2orf15 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,525 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C2orf15-associated GO terms across cancer lineages are Collagen fibril organization, Establishment of epithelial cell apical/basal polarity, and Establishment of apical/basal cell polarity. Each is linked with C2orf15 in more than 15 cancer types. Because this analysis shows association rather than direction, both C2orf15-to-partner and partner-to-C2orf15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Collagen fibril organization grouped by C2orf15-low versus C2orf15-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf15→partner) and Y-score (partner→C2orf15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCCollagen fibril organization →-0.303-1.870<.001.001316
LUNG_NSCLC_LUSCEstablishment of epithelial cell apical/basal polarity →-0.242-1.678<.001<.001314
PANCREASEstablishment of apical/basal cell polarity →-0.184-1.546<.001<.001314
LUNG_SCLCRegulation of collagen metabolic process →-0.169-1.555.001.002313
LIVERCarbohydrate biosynthetic process →-0.094-1.272<.001<.001313
LUNG_NSCLC_LUSCKeratinocyte development →-0.486-1.776<.001<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,525 associations by consensus.

Collagen fibril organization by C2orf15 expression — LUNG_NSCLC_LUSC

Box plot of Collagen fibril organization in C2orf15-low vs C2orf15-high samples in LUNG_NSCLC_LUSC.

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Exploration