Across TCGA cell cohorts, C2CD4D mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C2CD4D-associated genes across cancer lineages are BPIFA1, PRSS54, and OR5C1. Each is linked with C2CD4D in more than 1 cancer types. Because this analysis shows association rather than direction, both C2CD4D-to-partner and partner-to-C2CD4D results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2CD4D→partner) and Y-score (partner→C2CD4D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	BPIFA1 →	+0.995	+5.643	<.001	.002	3	2
LARGE_INTESTINE	PRSS54 →	+0.046	+3.930	<.001	.003	3	1
LARGE_INTESTINE	OR5C1 →	+0.042	+3.793	<.001	.007	3	1
LARGE_INTESTINE	BPIFB6 →	+0.020	+4.437	<.001	.004	3	1
LARGE_INTESTINE	OR2B2 →	+0.030	+4.347	.003	.001	3	1
LARGE_INTESTINE	FREM3 →	+0.135	+4.054	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

C2CD4D survival (RNA) · tumor vs normal (RNA) · all C2CD4D data types