C22orf46

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C22orf46 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,747 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible C22orf46-associated proteins across cancer lineages are SLIRP, TBRG4, and LRPPRC. Each is linked with C22orf46 in more than 4 cancer types. Because this analysis shows association rather than direction, both C22orf46-to-partner and partner-to-C22orf46 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf46→partner) and Y-score (partner→C22orf46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCASLIRP →-0.406-0.349.001.00835
COADTBRG4 →-0.382-0.477<.001<.00134
COADLRPPRC →-0.402-0.472<.001<.00134
OVPRKCD →-0.417-0.684<.001<.00133
UCECATL2 →-0.426-0.474.002.00133
LUADEIF4B →-0.293-0.516<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,747 associations by consensus.

Exploration