Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, C22orf46 mutation is significantly associated with the RNA expression of many other genes, with 3,308 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible C22orf46-associated genes across cancer lineages are TMEM263, FAM177A1, and CENPU. Each is linked with C22orf46 in more than 1 cancer types. Because this analysis shows association rather than direction, both C22orf46-to-partner and partner-to-C22orf46 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (C22orf46→partner) and Y-score (partner→C22orf46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.