Across TCGA cell cohorts, C22orf42 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C22orf42-associated genes across cancer lineages are GSG1L2, TBC1D3, and SLC36A3. Each is linked with C22orf42 in more than 1 cancer types. Because this analysis shows association rather than direction, both C22orf42-to-partner and partner-to-C22orf42 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf42→partner) and Y-score (partner→C22orf42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GSG1L2 →	+0.043	+4.969	<.001	.003	3	1
LARGE_INTESTINE	TBC1D3 →	+0.091	+4.273	<.001	.006	3	1
BLOOD_Leukemia	SLC36A3 →	+0.024	+4.564	.004	.003	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

C22orf42 survival (RNA) · tumor vs normal (RNA) · all C22orf42 data types