C22orf39

Across TCGA patient cohorts, C22orf39 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,703 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C22orf39-associated proteins across cancer lineages are ARVCF, NMI, and TRMT2A. Each is linked with C22orf39 in more than 5 cancer types. Because this analysis shows association rather than direction, both C22orf39-to-partner and partner-to-C22orf39 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C22orf39 versus ARVCF in UCEC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf39→partner) and Y-score (partner→C22orf39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARVCF →	+0.522	+0.451	.001	<.001	3	6
UCEC	NMI →	-0.500	-0.382	<.001	.001	3	6
OV	TRMT2A →	+0.263	+0.389	<.001	<.001	3	6
GBM	DTX3L →	-0.431	-0.496	.002	<.001	3	6
BRCA	ACTR2 →	-0.177	-0.430	.009	.001	3	5
GBM	CASP4 →	-0.621	-0.477	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,703 associations by consensus.

C22orf39 vs ARVCF — UCEC

Explore this scatter interactively →