C22orf39

Across TCGA patient cohorts, C22orf39 protein abundance is significantly associated with the RNA expression of many other genes, with 1,368 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C22orf39-associated genes across cancer lineages are ZMYM5, RNVU1-3, and RPL9P2. Each is linked with C22orf39 in more than 1 cancer types. Because this analysis shows association rather than direction, both C22orf39-to-partner and partner-to-C22orf39 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C22orf39 versus ZMYM5 in UCEC, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf39→partner) and Y-score (partner→C22orf39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZMYM5 →	+0.562	+0.804	.001	<.001	3	2
UCEC	RNVU1-3 →	+1.077	+0.718	.004	.001	3	2
UCEC	RPL9P2 →	+0.766	+0.612	.006	.002	3	2
UCEC	ZBED4 →	+0.563	+0.609	.003	.001	3	1
UCEC	DAAM1 →	+0.475	+0.564	.001	<.001	3	1
UCEC	PPP4R3A →	+0.532	+0.765	.007	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,368 associations by consensus.

C22orf39 vs ZMYM5 — UCEC

Explore this scatter interactively →