C22orf39

Across TCGA patient cohorts, C22orf39 protein abundance is significantly associated with the protein abundance of many other proteins, with 3,176 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C22orf39-associated proteins across cancer lineages are MBD1_S391, PLIN5_S277, and APBA3_S46. Each is linked with C22orf39 in more than 1 cancer types. Because this analysis shows association rather than direction, both C22orf39-to-partner and partner-to-C22orf39 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C22orf39 versus MBD1_S391 in LUAD, with a Pearson correlation of 0.66.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf39→partner) and Y-score (partner→C22orf39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MBD1_S391 →	+0.721	+0.945	<.001	.005	3	2
UCEC	PLIN5_S277 →	+2.384	+1.091	<.001	<.001	3	2
UCEC	APBA3_S46 →	+1.808	+1.076	<.001	.002	3	1
UCEC	ARFGAP1_S246 →	-0.686	-0.981	<.001	<.001	3	1
LUAD	ARAF_Y301 →	+1.128	+1.211	.002	<.001	3	1
CCRCC	APOO →	+0.486	+0.710	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,176 associations by consensus.

C22orf39 vs MBD1_S391 — LUAD

Explore this scatter interactively →