C22orf39

Across TCGA patient cohorts, C22orf39 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C22orf39-associated genes across cancer lineages are Monocytes, Pericytes, and Adipocytes. Each is linked with C22orf39 in more than 1 cancer types. Because this analysis shows association rather than direction, both C22orf39-to-partner and partner-to-C22orf39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocytes grouped by C22orf39-low versus C22orf39-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf39→partner) and Y-score (partner→C22orf39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Monocytes →	+0.048	+5.734	<.001	.027	3	1
COAD	Pericytes →	+0.135	+4.541	<.001	.017	3	1
UCEC	Adipocytes →	+0.025	+2.507	.020	.022	3	1
UCEC	pDC →	+0.067	+2.818	.024	.037	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Monocytes by C22orf39 expression — COAD

Explore this box plot interactively →