C22orf39

Across TCGA cell cohorts, C22orf39 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,845 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C22orf39-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and DNA replication-dependent chromatin assembly. Each is linked with C22orf39 in more than 15 cancer types. Because this analysis shows association rather than direction, both C22orf39-to-partner and partner-to-C22orf39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cellular anatomical structure grouped by C22orf39-low versus C22orf39-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf39→partner) and Y-score (partner→C22orf39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Symbiont-mediated disruption of host cellular anatomical structure →	+0.128	+0.715	<.001	<.001	3	16
KIDNEY	Symbiont-mediated disruption of host anatomical structure →	+0.128	+0.715	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	DNA replication-dependent chromatin assembly →	+0.119	+0.817	.001	<.001	3	11
PANCREAS	Positive regulation of mitochondrial membrane permeability involved in apoptotic process →	+0.087	+0.597	.004	.001	3	10
BLOOD_Lymphoma	Viral RNA genome replication →	+0.149	+0.686	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of macrophage proliferation →	+0.180	+0.652	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,845 associations by consensus.

Symbiont-mediated disruption of host cellular anatomical structure by C22orf39 expression — KIDNEY

Explore this box plot interactively →