Across TCGA patient cohorts, C22orf34 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C22orf34-associated genes across cancer lineages are PINCR, MIR596, and LINC00351. Each is linked with C22orf34 in more than 1 cancer types. Because this analysis shows association rather than direction, both C22orf34-to-partner and partner-to-C22orf34 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf34→partner) and Y-score (partner→C22orf34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PINCR →	+0.557	+4.120	<.001	.002	3	2
COAD	MIR596 →	+1.025	+3.776	<.001	.006	3	1
COAD	LINC00351 →	+0.305	+3.899	<.001	.003	3	1
COAD	CDC42P2 →	+0.198	+3.911	.001	.004	3	1
COAD	NREP-AS1 →	+0.289	+4.496	<.001	<.001	3	1
COAD	MIR4470 →	+0.603	+3.515	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

C22orf34 survival (RNA) · tumor vs normal (RNA) · all C22orf34 data types