Across TCGA cell cohorts, C22orf34 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible C22orf34-associated genes across cancer lineages are FAM47B, LCE1C, and LCE1F. Each is linked with C22orf34 in more than 1 cancer types. Because this analysis shows association rather than direction, both C22orf34-to-partner and partner-to-C22orf34 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf34→partner) and Y-score (partner→C22orf34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	FAM47B →	+0.016	+5.029	<.001	.006	3	1
LUNG_SCLC	LCE1C →	+0.896	+5.643	<.001	.002	3	1
LUNG_SCLC	LCE1F →	+0.143	+5.643	<.001	.002	3	1
LUNG_NSCLC_LUAD	CFHR5 →	+0.011	+4.093	<.001	.004	3	1
LUNG_NSCLC_LUAD	SULT6B1 →	+0.970	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	H2BC1 →	+0.504	+3.544	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

C22orf34 survival (RNA) · tumor vs normal (RNA) · all C22orf34 data types