C22orf23

Across TCGA patient cohorts, C22orf23 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,578 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C22orf23-associated proteins across cancer lineages are MICALL1, MICALL1_S621, and ST13. Each is linked with C22orf23 in more than 5 cancer types. Because this analysis shows association rather than direction, both C22orf23-to-partner and partner-to-C22orf23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C22orf23 versus MICALL1 in LSCC, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf23→partner) and Y-score (partner→C22orf23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MICALL1 →	+0.400	+0.725	<.001	<.001	3	6
LSCC	MICALL1_S621 →	+0.816	+0.576	<.001	<.001	3	5
GBM	ST13 →	+0.352	+0.478	<.001	<.001	3	5
BRCA	FSCN1 →	+0.669	+0.474	<.001	.003	3	5
BRCA	RBM47 →	-0.308	-0.368	<.001	<.001	3	4
LSCC	KRT5 →	+1.357	+0.643	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,578 associations by consensus.

C22orf23 vs MICALL1 — LSCC

Explore this scatter interactively →