C20orf85

Across TCGA patient cohorts, C20orf85 mutation is significantly associated with the RNA expression of many other genes, with 108 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible C20orf85-associated genes across cancer lineages are RNU5E-7P, MIR6783, and RNU6-752P. Each is linked with C20orf85 in more than 1 cancer types. Because this analysis shows association rather than direction, both C20orf85-to-partner and partner-to-C20orf85 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU5E-7P grouped by C20orf85-low versus C20orf85-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C20orf85→partner) and Y-score (partner→C20orf85) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU5E-7P →	+0.408	+4.453	<.001	.006	3	2
UCEC	MIR6783 →	+0.791	+3.517	.002	.005	3	2
SKCM	RNU6-752P →	+0.160	+3.990	<.001	.009	3	2
SKCM	RNA5SP461 →	+0.173	+6.009	<.001	<.001	3	2
LUAD	KRTAP6-1 →	+0.057	+6.108	<.001	.001	3	1
LUAD	RNU1-7P →	+0.241	+4.855	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 108 associations by consensus.

RNU5E-7P by C20orf85 expression — UCEC

Explore this box plot interactively →