C20orf27

Across TCGA patient cohorts, C20orf27 protein abundance is significantly associated with the RNA expression of many other genes, with 4,977 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C20orf27-associated genes across cancer lineages are CPT2, CDC25B, and ITPA. Each is linked with C20orf27 in more than 3 cancer types. Because this analysis shows association rather than direction, both C20orf27-to-partner and partner-to-C20orf27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C20orf27 versus CPT2 in CCRCC, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C20orf27→partner) and Y-score (partner→C20orf27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CPT2 →	-0.329	-0.181	<.001	<.001	3	4
COAD	CDC25B →	+1.144	+0.411	<.001	<.001	3	4
COAD	ITPA →	+0.791	+0.403	<.001	<.001	3	4
OV	NXT1 →	+0.498	+0.398	<.001	.001	3	4
PDAC	CEACAM3 →	+0.620	+0.250	<.001	<.001	3	4
COAD	NDUFAF5 →	+0.503	+0.253	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,977 associations by consensus.

C20orf27 vs CPT2 — CCRCC

Explore this scatter interactively →