C20orf27

Across TCGA patient cohorts, C20orf27 mutation is significantly associated with the RNA expression of many other genes, with 1,217 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C20orf27-associated genes across cancer lineages are RNU6-1336P, TRAJ21, and SNX3P1X. Each is linked with C20orf27 in more than 2 cancer types. Because this analysis shows association rather than direction, both C20orf27-to-partner and partner-to-C20orf27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1336P grouped by C20orf27-low versus C20orf27-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C20orf27→partner) and Y-score (partner→C20orf27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-1336P →	+0.297	+4.235	.001	.003	3	3
UCEC	TRAJ21 →	+0.674	+3.129	<.001	<.001	3	3
UCEC	SNX3P1X →	+0.211	+3.034	<.001	.008	3	3
COAD	RPL5P16 →	+0.266	+4.893	<.001	.005	3	2
HNSC	RNA5SP64 →	+0.353	+7.954	<.001	.008	3	2
LUSC	OR2A41P →	+0.236	+4.393	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,217 associations by consensus.

RNU6-1336P by C20orf27 expression — LUSC

Explore this box plot interactively →