C20orf181

Across TCGA pan-cancer cohorts, C20orf181 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of C20orf181’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where C20orf181 RNA is repressed in tumor relative to normal tissue. In most cancer types C20orf181 is over-expressed in tumor, although a few such as UCEC show the opposite, repressed pattern.

UCEC and BRCA are the cancer types where C20orf181 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C20orf181 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	−0.149	.027	2	view →
BRCA	Female	All	+0.029	.033	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

C20orf181–UCEC

Open the UCEC breakdown →