C20orf141

Across TCGA patient cohorts, C20orf141 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,059 significant associations in total. STAD shows the largest number of these associations.

The most reproducible C20orf141-associated GO terms across cancer lineages are Negative regulation of interleukin-10 production, Positive regulation of T cell mediated immunity, and Positive regulation of type 2 immune response. Each is linked with C20orf141 in more than 19 cancer types. Because this analysis shows association rather than direction, both C20orf141-to-partner and partner-to-C20orf141 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of interleukin-10 production grouped by C20orf141-low versus C20orf141-high in BLCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C20orf141→partner) and Y-score (partner→C20orf141) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	Negative regulation of interleukin-10 production →	+0.069	+0.482	<.001	<.001	3	20
ESCA	Positive regulation of T cell mediated immunity →	+0.040	+0.252	<.001	<.001	3	19
ESCA	Positive regulation of type 2 immune response →	+0.071	+0.295	<.001	<.001	3	19
ESCA	Type II interferon production →	+0.041	+0.236	<.001	<.001	3	19
ESCA	Interleukin-10 production →	+0.041	+0.217	<.001	<.001	3	19
ESCA	Regulation of CD4-positive, alpha-beta T cell activation →	+0.041	+0.203	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,059 associations by consensus.

Negative regulation of interleukin-10 production by C20orf141 expression — BLCA

Explore this box plot interactively →