C1orf94

Across TCGA cell cohorts, C1orf94 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C1orf94-associated genes across cancer lineages are OR56A1, SPEM3, and GPR26. Each is linked with C1orf94 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf94-to-partner and partner-to-C1orf94 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR56A1 grouped by C1orf94-low versus C1orf94-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf94→partner) and Y-score (partner→C1orf94) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR56A1 →	+0.262	+3.604	<.001	.004	3	2
BLOOD_Leukemia	SPEM3 →	+0.012	+4.824	<.001	<.001	3	2
OESOPHAGUS	GPR26 →	+0.036	+4.906	<.001	.006	3	1
OESOPHAGUS	C10orf71 →	+0.006	+4.906	<.001	.006	3	1
URINARY_TRACT	PCDH11Y →	+0.016	+5.087	<.001	.004	3	1
LARGE_INTESTINE	ADRA1A →	+0.228	+3.688	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

OR56A1 by C1orf94 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →