C1orf50

Across TCGA patient cohorts, C1orf50 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,034 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C1orf50-associated proteins across cancer lineages are ERI3, NUMA1, and YTHDC1. Each is linked with C1orf50 in more than 6 cancer types. Because this analysis shows association rather than direction, both C1orf50-to-partner and partner-to-C1orf50 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf50 versus ERI3 in BRCA, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf50→partner) and Y-score (partner→C1orf50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ERI3 →	+0.324	+0.409	<.001	<.001	3	7
LSCC	NUMA1 →	+0.300	+0.333	.005	<.001	3	5
GBM	YTHDC1 →	+0.270	+0.244	<.001	<.001	3	5
GBM	NRF1 →	+0.380	+0.305	<.001	.001	3	5
GBM	KHDRBS1 →	+0.280	+0.280	.002	.004	3	5
LSCC	SNRNP40 →	+0.161	+0.298	.002	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,034 associations by consensus.

C1orf50 vs ERI3 — BRCA

Explore this scatter interactively →